Structure of PDB 3jqp Chain C

Receptor sequence

>3jqpC (length=265) Species: 5833 (Plasmodium falciparum) [Search protein sequence]

NFINLYTVKNPLKCKIVDKINLVRPNSPNEVYHLEINHNGLFKYLEGHTC
GIIPYYNEQRCARLYSISSSNNMENLSVAIKIHKYETNYGYCSGFIKNLK
INDDIYLTGAHGYFNLPNDAIQKNTNFIFIATGTGISPYISFLKKLFAYD
KNNLYNRNSNYTGYITIYYGVYNEDSILYLNELEYFQKMYPNNINIHYVF
SYKDATSFYVQDEIYKRKTEFLNLFNNYKCELYICGLKSIRYKVMDILKS
HDDEKKKKRVHVEVY

3D structure

PDB

3jqp Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis

Chain

Resolution

3.0 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	Y103 S104 C284 E314 Y316
Catalytic site (residue number reindexed from 1)	Y65 S66 C235 E263 Y265
Enzyme Commision number	1.18.1.2: ferredoxin--NADP(+) reductase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	FAD	C	R101 L102 Y103 S104 A117 K119 H121 Y123 G136 Y137 C138 S139 T180 E314 Y316	R63 L64 Y65 S66 A79 K81 H83 Y85 G90 Y91 C92 S93 T134 E263 Y265
BS02	A2P	C	K119 G179 V217 Y218 S247 Y258 Q260 L286 S288	K81 G133 V171 Y172 S201 Y209 Q211 L237 S239
BS03	A2P	C	Y258 K287 S288	Y209 K238 S239

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity

View graph for
Molecular Function

External links

PDB	RCSB:3jqp, PDBe:3jqp, PDBj:3jqp
PDBsum	3jqp
PubMed	19736991
UniProt	C6KT68\|FENR_PLAF7 Ferredoxin--NADP reductase, apicoplast (Gene Name=FNR)

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