Structure of PDB 3irq Chain C

Receptor sequence
>3irqC (length=64) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKL
QKEAGTPPLWKIAV
3D structure
PDB3irq Crystal structure of a junction between two Z-DNA helices.
ChainC
Resolution2.8 Å
3D
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Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K170 N173 R174 Y177 T191 P192 P193 K35 N38 R39 Y42 T56 P57 P58
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity

View graph for
Molecular Function
External links
PDB RCSB:3irq, PDBe:3irq, PDBj:3irq
PDBsum3irq
PubMed20439751
UniProtP55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)

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