Structure of PDB 3iqe Chain C

Receptor sequence
>3iqeC (length=282) Species: 2320 (Methanopyrus kandleri) [Search protein sequence]
TVAKAIFIKCGNLGTSMMMDMLLDERADREDVEFRVVGTSVKMDPECVEA
AVEMALDIAEDFEPDFIVYGGPNPAAPGPSKAREMLADSEYPAVIIGDAP
GLKVKDEMEEQGLGYILVKPDAMLGARREFLDPVEMAIYNADLMKVLAAT
GVFRVVQEAFDELIEKAKEDEISENDLPKLVIDRNTLLEREEFENPYAMV
KAMAALEIAENVADVSVEGCFVEQDKERYVPIVASAHEMMRKAAELADEA
RELEKSNDAVLRTPHAPDGKVLSKRKFMEDPE
3D structure
PDB3iqe Structural basis of the hydride transfer mechanism in F(420)-dependent methylenetetrahydromethanopterin dehydrogenase
ChainC
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.5.98.1: methylenetetrahydromethanopterin dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 H4M C N13 L14 M124 L125 A127 R128 R129 E130 M137 N141 C221 F222 Y230 N12 L13 M123 L124 A126 R127 R128 E129 M136 N140 C220 F221 Y229
BS02 F42 C G12 L14 M44 P73 N74 D99 M124 F222 G11 L13 M43 P72 N73 D98 M123 F221
BS03 H4M C E26 R27 A28 E25 R26 A27
Gene Ontology
Molecular Function
GO:0008901 ferredoxin hydrogenase activity
GO:0016491 oxidoreductase activity
GO:0030268 methylenetetrahydromethanopterin dehydrogenase activity
Biological Process
GO:0006730 one-carbon metabolic process
GO:0015948 methanogenesis
GO:0019386 methanogenesis, from carbon dioxide

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Molecular Function
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Biological Process
External links
PDB RCSB:3iqe, PDBe:3iqe, PDBj:3iqe
PDBsum3iqe
PubMed19761261
UniProtP94951|MTD_METKA F420-dependent methylenetetrahydromethanopterin dehydrogenase (Gene Name=mtd)

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