Structure of PDB 3io8 Chain C

Receptor sequence
>3io8C (length=146) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRY
RRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALC
VESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN
3D structure
PDB3io8 Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands.
ChainC
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C F97 Y101 A104 F105 Q111 L112 S122 Q125 V126 E129 L130 R132 D133 N136 G138 R139 F146 Y195 F46 Y50 A53 F54 Q60 L61 S71 Q74 V75 E78 L79 R81 D82 N85 G87 R88 F95 Y144
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:3io8, PDBe:3io8, PDBj:3io8
PDBsum3io8
PubMed19726685
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

[Back to BioLiP]