Structure of PDB 3inn Chain C

Receptor sequence
>3innC (length=284) Species: 29459 (Brucella melitensis) [Search protein sequence]
SMQIIHTIEELRQALAPARQQGKKIGFVPTMGYLHKGHLELVRRARVEND
VTLVSIFVNPLQFGANEDLGRYPRDLERDAGLLHDAQVDYLFAPTVSDMY
PRPMQTVVDVPPLGNQIEGEARPGHFAGVATVVSKLFNIVGPDAAYFGEK
DFQQLVIIRRMVDDMAIPVRIVGVETVREDDGLACSSRNVYLTPEQRRAA
IIVPQALDEADRLYRSGMDDPDALEAAIRTFIGRQPLAVPEVIAIRDPET
LERLPALQGRPILVALFVRVGATRLLDNRVIGHA
3D structure
PDB3inn Crystal structure of pantoate-beta-alanine-ligase in complex with ATP at low occupancy at 2.1 A resolution
ChainC
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) M30 H34 H37 R77 D78 L81 K149 S185 S186 R187
Catalytic site (residue number reindexed from 1) M31 H35 H38 R78 D79 L82 K150 S186 S187 R188
Enzyme Commision number 6.3.2.1: pantoate--beta-alanine ligase (AMP-forming).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C P28 T29 M30 H34 H37 L40 Q61 F146 G147 K149 D150 Q153 T175 V176 C184 P29 T30 M31 H35 H38 L41 Q62 F147 G148 K150 D151 Q154 T176 V177 C185
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004592 pantoate-beta-alanine ligase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0009058 biosynthetic process
GO:0015940 pantothenate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3inn, PDBe:3inn, PDBj:3inn
PDBsum3inn
PubMed
UniProtQ8YFC9|PANC_BRUME Pantothenate synthetase (Gene Name=panC)

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