Structure of PDB 3in7 Chain C

Receptor sequence
>3in7C (length=100) Species: 9606 (Homo sapiens) [Search protein sequence]
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQV
3D structure
PDB3in7 Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
ChainC
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AYQ C R67 R86 S88 S90 S96 H107 F108 K109 L120 W121 R13 R32 S34 S36 S42 H53 F54 K55 L66 W67 MOAD: Ka=1200000M^-1
External links
PDB RCSB:3in7, PDBe:3in7, PDBj:3in7
PDBsum3in7
PubMed19886660
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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