Structure of PDB 3ihk Chain C

Receptor sequence
>3ihkC (length=207) Species: 1309 (Streptococcus mutans) [Search protein sequence]
TKVALFSGGDLTYFTRDFDYFVGIDKGSSFLLKNQLPLDLAIGDFDSVSA
EEFKQIKAKAKKLVMAPAEKNDTDTELALKTIFDCFGRVEIIVFGAFGGR
IDHMLSNIFLPSDPDLAPFMRCFKLRDEQNLVEFFPAGQHQIEQATDMVY
ISFMAANGAHLSIQDAKYELTEENYFQKKIYSSNEFKDKPICFSVASGYV
VVIQTKD
3D structure
PDB3ihk Northeast Structural Genomics Consortium Target SmR83
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.6.2: thiamine diphosphokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TPP C Y169 Y182 S183 S184 N185 Y168 Y181 S182 S183 N184
BS02 TPP C K71 N72 D73 D75 R101 H104 K70 N71 D72 D74 R100 H103
BS03 MG C D26 D45 D47 D75 D25 D44 D46 D74
Gene Ontology
Molecular Function
GO:0004788 thiamine diphosphokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0030975 thiamine binding
GO:0046872 metal ion binding
Biological Process
GO:0006772 thiamine metabolic process
GO:0009229 thiamine diphosphate biosynthetic process
GO:0016310 phosphorylation
GO:0042723 thiamine-containing compound metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3ihk, PDBe:3ihk, PDBj:3ihk
PDBsum3ihk
PubMed
UniProtQ8DVV9

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