Structure of PDB 3hr4 Chain C

Receptor sequence
>3hr4C (length=188) Species: 9606 (Homo sapiens) [Search protein sequence]
EIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLGALF
SCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKLKKSLFM
LKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDE
LSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYT
3D structure
PDB3hr4 Regulation of Interdomain Interactions by CaM in Inducible Nitric Oxide Synthase
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.39: nitric-oxide synthase (NADPH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN C N595 G596 D597 N84 G85 D86
BS02 FMN C T545 E546 T547 K549 S550 S591 T592 F593 G594 N595 G627 S628 Y631 R633 F634 C635 E661 T34 E35 T36 K38 S39 S80 T81 F82 G83 N84 G116 S117 Y120 R122 F123 C124 E150
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3hr4, PDBe:3hr4, PDBj:3hr4
PDBsum3hr4
PubMed
UniProtP35228|NOS2_HUMAN Nitric oxide synthase, inducible (Gene Name=NOS2)

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