Structure of PDB 3hb1 Chain C

Receptor sequence
>3hb1C (length=258) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFN
LADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFGGVDWMRKL
AFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLK
ALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALR
HALELEYL
3D structure
PDB3hb1 Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
ChainC
Resolution2.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AF3 C D274 D276 T447 T448 K480 D10 D12 T167 T168 K200
BS02 MG C D274 D276 D502 D10 D12 D222
Gene Ontology
Molecular Function
GO:0004725 protein tyrosine phosphatase activity
Biological Process
GO:0007275 multicellular organism development

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Molecular Function
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Biological Process
External links
PDB RCSB:3hb1, PDBe:3hb1, PDBj:3hb1
PDBsum3hb1
PubMed19858093
UniProtO00167|EYA2_HUMAN Eyes absent homolog 2 (Gene Name=EYA2)

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