Structure of PDB 3gs2 Chain C

Receptor sequence
>3gs2C (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
SEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALEELR
SKGESNQMNLDTEKQYTIYIATASGQFTVLDGSFSLELVSEKYWKVNKPM
ELYYAPTK
3D structure
PDB3gs2 Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain.
ChainC
Resolution1.699 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C S224 E225 E227 R246 Y247 I248 K249 T250 H258 K261 Y262 R266 N322 K323 P324 S1 E2 E4 R23 Y24 I25 K26 T27 H35 K38 Y39 R43 N97 K98 P99
Gene Ontology
Cellular Component
GO:0000151 ubiquitin ligase complex

View graph for
Cellular Component
External links
PDB RCSB:3gs2, PDBe:3gs2, PDBj:3gs2
PDBsum3gs2
PubMed20696397
UniProtQ99496|RING2_HUMAN E3 ubiquitin-protein ligase RING2 (Gene Name=RNF2)

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