Structure of PDB 3ggg Chain C

Receptor sequence
>3gggC (length=281) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
LKSLSMQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDL
GIIDEGTTSIAKVEDFSPDFVMLSSPVRTFREIAKKLSYILSEDATVTDQ
GSVKGKLVYDLENILGKRFVGGHPIAGTEKSGVEYSLDNLYEGKKVILTP
TKKTDKKRLKLVKRVWEDVGGVVEYMSPELHDYVFGVVSHLPHAVAFALV
DTLIHMSTPEVDLFKYPGGGFKDFTRIAKSDPIMWRDIFLENKENVMKAI
EGFEKSLNHLKELIVREAEEELVEYLKEVKI
3D structure
PDB3ggg The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
ChainC
Resolution2.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD C V38 F40 M41 D62 I63 S67 S98 S99 P100 T103 Q124 S126 A150 M258 V14 F16 M17 D38 I39 S43 S74 S75 P76 T79 Q100 S102 A126 M234
BS02 TYR C S126 H147 T152 R250 I251 S102 H123 T128 R226 I227
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004665 prephenate dehydrogenase (NADP+) activity
GO:0008977 prephenate dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0070403 NAD+ binding
Biological Process
GO:0006571 tyrosine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3ggg, PDBe:3ggg, PDBj:3ggg
PDBsum3ggg
PubMed19279014
UniProtO67636

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