Structure of PDB 3fs4 Chain C

Receptor sequence

>3fs4C (length=141) Species: 8801 (Struthio camelus)

VLSGTDKTNVKGIFSKISSHAEEYGAETLERMFITYPQTKTYFPHFDLHH
GSAQIKAHGKKVANALIEAVNHIDDISGALSKLSDLHAQKLRVDPVNFKL
LGQCFLVVVAIHHPSALTPEVHASLDKFLCAVGAVLTAKYR

3D structure

• PDB: 3fs4 Structural studies of hemoglobin from two flightless birds, ostrich and turkey: insights into their differing oxygen-binding properties.
• Chain: C
• Resolution: 2.22 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	C	Y42 F43 H45 H58 V62 L83 L86 H87 L91 N97 F98 L136	Y42 F43 H45 H58 V62 L83 L86 H87 L91 N97 F98 L136

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0005506 iron ion binding
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0031720 haptoglobin binding
• GO:0043177 organic acid binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015671 oxygen transport
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005833 hemoglobin complex
• GO:0031838 haptoglobin-hemoglobin complex
• GO:0072562 blood microparticle

External links

• PDB: RCSB:3fs4, PDBe:3fs4, PDBj:3fs4
• PDBsum: 3fs4
• PubMed: 33950023
• UniProt: P01981|HBA_STRCA Hemoglobin subunit alpha-A (Gene Name=HBAA)