Structure of PDB 3fcu Chain C

Receptor sequence
>3fcuC (length=451) Species: 9606 (Homo sapiens) [Search protein sequence]
NLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETG
GVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWS
DVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTL
SRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVA
DIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTT
EYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGD
GRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQ
LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRS
RPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQ
P
3D structure
PDB3fcu Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces.
ChainC
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C E243 D245 D247 T250 E252 E242 D244 D246 T249 E251
BS02 CA C D297 N299 D301 R303 D305 D296 N298 D300 R302 D304
BS03 CA C D365 D367 D369 Y371 D373 D364 D366 D368 Y370 D372
BS04 CA C D426 D428 N430 Y432 D434 D425 D427 N429 Y431 D433
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3fcu, PDBe:3fcu, PDBj:3fcu
PDBsum3fcu
PubMed19111664
UniProtP08514|ITA2B_HUMAN Integrin alpha-IIb (Gene Name=ITGA2B)

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