Structure of PDB 3fat Chain C

Receptor sequence
>3fatC (length=260) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYK
IAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDF
SKPFMSLGISIMIKKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKI
AVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQ
RKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKN
KWWYDKGECG
3D structure
PDB3fat Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4
ChainC
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMQ C Y59 T89 R94 L136 S140 T141 L190 E191 Y59 T89 R94 L136 S140 T141 L190 E191 MOAD: Kd=22.8nM
BindingDB: Ki=40nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3fat, PDBe:3fat, PDBj:3fat
PDBsum3fat
PubMed19022251
UniProtP19493|GRIA4_RAT Glutamate receptor 4 (Gene Name=Gria4)

[Back to BioLiP]