Structure of PDB 3f78 Chain C

Receptor sequence
>3f78C (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
GNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSY
KTEFDFSDYVKWKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGAR
PDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKF
ASKPASEFVKILDTFEKLKDLFTELQKKIY
3D structure
PDB3f78 Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems.
ChainC
Resolution1.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG C S139 S141 D239 S12 S14 D112
External links
PDB RCSB:3f78, PDBe:3f78, PDBj:3f78
PDBsum3f78
PubMed19332643
UniProtP20701|ITAL_HUMAN Integrin alpha-L (Gene Name=ITGAL)

[Back to BioLiP]