Structure of PDB 3e1i Chain C

Receptor sequence
>3e1iC (length=288) Species: 9606 (Homo sapiens) [Search protein sequence]
SSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQ
DIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDF
KKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWN
GRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFF
TSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTY
SKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRL
3D structure
PDB3e1i Fibrinogen variant BbetaD432A has normal polymerization but does not bind knob "B".
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C D298 D301 T305 F322 Q329 D330 K338 C339 H340 Y363 D364 D194 D197 T201 F218 Q225 D226 K234 C235 H236 Y259 D260
BS02 CA C D318 D320 F322 G324 D214 D216 F218 G220
BS03 CA C D294 G296 D298 D301 D190 G192 D194 D197
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e1i, PDBe:3e1i, PDBj:3e1i
PDBsum3e1i
PubMed19075185
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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