Structure of PDB 3dxc Chain C

Receptor sequence
>3dxcC (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
FQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTI
LHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPN
AASLSEAVQAACMLRYQKCLDAR
3D structure
PDB3dxc Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C V559 R607 L609 S610 F611 L612 A613 V614 G615 R616 V618 A644 E648 Q651 C654 R657 Y658 C661 L662 R665 V17 R65 L67 S68 F69 L70 A71 V72 G73 R74 V76 A102 E106 Q109 C112 R115 Y116 C119 L120 R123
Gene Ontology
Molecular Function
GO:0001540 amyloid-beta binding

View graph for
Molecular Function
External links
PDB RCSB:3dxc, PDBe:3dxc, PDBj:3dxc
PDBsum3dxc
PubMed18833287
UniProtO00213|APBB1_HUMAN Amyloid beta precursor protein binding family B member 1 (Gene Name=APBB1)

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