Structure of PDB 3csw Chain C

Receptor sequence
>3cswC (length=275) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
HHVLIWWRGKFRRADEISLDFSLFEKSLQGAVYETLRTYSRAPFAAYKHY
TRLKRSADFFNLPLSLSFDEFTKVLKAGADEFKQEVRIKVYLFPDSGEVL
FVFSPLNIPDLETGVEVKISNVRRIPDLSTPPALKITGRTDIVLARREIV
DCYDVILLGLNGQVCEGSFSNVFLVKEGKLITPSLDSGILDGITRENVIK
LAKSLEIPVEERVVWVWELFEADEMFLTHTSAGVVPVRRLNEHSFFEEEP
GPVTATLMENFEPFVLNLEENWVGI
3D structure
PDB3csw Crystal structure of a Putative Branched-Chain Amino Acid Aminotransferase (TM0831) from Thermotoga maritima at 2.15 A resolution
ChainC
Resolution2.15 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) Y31 K133 E164 L188
Catalytic site (residue number reindexed from 1) Y33 K135 E166 L190
Enzyme Commision number 2.6.1.42: branched-chain-amino-acid transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP C R50 K133 E164 F167 S168 L188 G190 I191 T192 T228 R52 K135 E166 F169 S170 L190 G192 I193 T194 T230
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0052654 L-leucine-2-oxoglutarate transaminase activity
GO:0052655 L-valine-2-oxoglutarate transaminase activity
GO:0052656 L-isoleucine-2-oxoglutarate transaminase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009098 L-leucine biosynthetic process
GO:0009099 L-valine biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3csw, PDBe:3csw, PDBj:3csw
PDBsum3csw
PubMed
UniProtP74921|ILVE_THEMA Probable branched-chain-amino-acid aminotransferase (Gene Name=ilvE)

[Back to BioLiP]