Structure of PDB 3btr Chain C

Receptor sequence
>3btrC (length=427) Species: 10090 (Mus musculus) [Search protein sequence]
NQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAG
LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFIS
LLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLS
TLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLA
DSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGN
IVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQ
IQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC
GIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGG
LDKIEALQRHENESVYKASLNLIEKYF
3D structure
PDB3btr Structural basis for the nuclear import of the human androgen receptor
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C R106 E107 W142 N146 A148 S149 G150 T151 T155 Q181 W184 N188 D192 R227 W231 R238 E266 D270 R37 E38 W73 N77 A79 S80 G81 T82 T86 Q112 W115 N119 D123 R158 W162 R169 E197 D201
External links
PDB RCSB:3btr, PDBe:3btr, PDBj:3btr
PDBsum3btr
PubMed18319300
UniProtP52293|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)

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