Structure of PDB 3aw9 Chain C

Receptor sequence

>3aw9C (length=299) Species: 410359 (Pyrobaculum calidifontis JCM 11548)

MRIVVTGGAGFIGSHLVDKLVELGYEVVVVDIVQRDAELHVRDLKDYSWG
AGIKGDVVFHFAANPEVRTEPIVHFNENVVATFNVLEWARQTGVRTVVFA
SSSTVYGDADVIPTPEEEPYKPISVYGAAKAAGEVMCATYARLFGVRCLA
VRYANVVGPRLRHGVIYDFIMKLRRNPNVLEVLGDGTQRKSYLYVRDAVE
ATLAAWKKFEEMDAPFLALNVGNVDAVRVLDIAQIVAEVLGLRPEIRLVP
STPDGRGWPGDVKYMTLAVTKLMKLTGWRPTMTSAEAVKKTAEDLAKEL

3D structure

• PDB: 3aw9 Structure of UDP-galactose 4-epimerase mutant
• Chain: C
• Resolution: 2.3 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): A2107 S2109 S2110 T2111 Y2133 K2137 L2168 G2171
• Catalytic site (residue number reindexed from 1): A100 S102 S103 T104 Y126 K130 L161 G164

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GDU	C	P2069 V2071 S2109 Y2133 N2162 L2190 Q2195 K2197 Y2199 V2236 W2265 D2268	P65 V67 S102 Y126 N155 L183 Q188 K190 Y192 V229 W258 D261
BS02	NAD	C	G2007 G2010 F2011 I2012 D2031 I2032 R2046 D2047 L2048 F2065 A2066 A2067 P2069 E2084 A2107 S2108 Y2133 K2137 Y2160 N2162 V2163 H2170	G7 G10 F11 I12 D31 I32 R42 D43 L44 F61 A62 A63 P65 E77 A100 S101 Y126 K130 Y153 N155 V156 H163

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003978 UDP-glucose 4-epimerase activity
• GO:0016491 oxidoreductase activity

Biological Process

• GO:0033499 galactose catabolic process via UDP-galactose

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:3aw9, PDBe:3aw9, PDBj:3aw9
• PDBsum: 3aw9
• UniProt: A3MUJ4