Structure of PDB 3al0 Chain C

Receptor sequence
>3al0C (length=564) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
KVTKDLVLHLENLARLELSEDQRESLMKDFQEILDYVELLNEVDVEGVEP
MYTPVEDSAKLRKGDPRFFEMRDLIKKNFPEEKDGHIKVPGIPKKIRRCF
ELVRVRFAPSPTGHLHVGGARTALFNWMFARKEGGKFILRIEDTDTERSS
REYEQQILESLRWCGLDWDEGPDIGGDFGPYRQSERLEIYREYAEKLVED
KRAYYVVYDKEDPSKELFTTYEYPHEYKEKGHPVTIKFKVLPGKTSFEDL
LKGYMEFDNSTLEDFIIMKSNGFPTYNFAVVVDDHLMRISHVFRGEDHLS
NTPKQLMIYEAFGWEAPVFMHIPLILGSDRTPLSKRHGATSVEHFRREGI
LSRALMNYLALLGWRVEGDEIFTIEEKLQSFDPKDISNKGVIFDYQKLEW
VNGKHMRRIDLEDLKREFIEWAKYAGKEIPSVDERYFSETLRICREKVNT
LSQLYDIMYPFMNDDYEYEKDYVEKFLKREEAERVLEEAKKAFKDLNSWN
MEEIEKTLRDLSEKGLASKKVVFQLIRGAVTGKLVTPGLFETIEVLGKER
TLKRLERTLQFLKK
3D structure
PDB3al0 Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions.
ChainC
Resolution3.368 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S136 K361
Catalytic site (residue number reindexed from 1) S110 K335
Enzyme Commision number 6.1.1.17: glutamate--tRNA ligase.
6.3.5.-
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004818 glutamate-tRNA ligase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0050566 asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006424 glutamyl-tRNA aminoacylation
GO:0006450 regulation of translational fidelity
GO:0043039 tRNA aminoacylation
GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3al0, PDBe:3al0, PDBj:3al0
PDBsum3al0
PubMed20882017
UniProtQ9WY94;
Q9X2I8|SYE2_THEMA Glutamate--tRNA ligase 2 (Gene Name=gltX2)

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