Structure of PDB 3ac0 Chain C

Receptor sequence
>3ac0C (length=831) Species: 4911 (Kluyveromyces marxianus) [Search protein sequence]
KFDVEQLLSELNQDEKISLLSAVDFWHTKKIERLGIPAVRVSDGPNGIRG
TKFFDGVPSGCFPNGTGLASTFDRDLLETAGKLMAKESIAKNAAVILGPT
TNMQRGPLGGRGFESFSEDPYLAGMATSSVVKGMQGEGIAATVKHFVCND
LEDQRFSSNSIVSERALREIYLEPFRLAVKHANPVCIMTAYNKVNGEHCS
QSKKLLIDILRDEWKWDGMLMSDWFGTYTTAAAIKNGLDIEFPGPTRWRT
RALVSHSLNSREQITTEDVDDRVRQVLKMIKFVVDNLEKTGIVENGPEST
SNNTKETSDLLRKIAADSIVLLKNKNNILPLKKEDNIIVIGPNAKAKTSS
GGGSASMNSYYVVSPYEGIVNKLGKEVDYTVGAYSHKSIGGLAESSLIDA
AKPENSGLIAKFYSNPVEERSDDEEPFHVTKVNRSNVHLFDFKHVDPKNP
YFFVTLTGQYVPQEDGDYIFSLQVYGSGLFYLNDELIIDQKQERGSFCFG
AGTKERTKKLTLKKGQVYNVRVEYGSGPTSFGAGGFQAGVIKAIDDDEEI
RNAAELAAKHDKAVLIIGLNGEWETEGYDRENMDLPKRTNELVRAVLKAN
PNTVIVNQSGTPVEFPWLEDANALVQAWYGGNELGNAIADVLYGDVVPNG
KLSLSWPFKLQDNPAFLNFKTEFGRVIYGEDIFVGYRYYEKLQRKVAFPF
GYGLSYTTFELDISDFKVTDDKIAISVDVKNTGDKFAGSEVVQVYFSALN
SKVSRPVKELKGFEKVHLEPGEKKTVNIDLELKDAISYFNEELGKWHVEA
GEYLVSVGTSSDDILSVKEFKVEKELYWKGL
3D structure
PDB3ac0 Role of a PA14 domain in determining substrate specificity of a glycoside hydrolase family 3 beta-glucosidase from Kluyveromyces marxianus.
ChainC
Resolution2.54 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D225 E588
Catalytic site (residue number reindexed from 1) D223 E574
Enzyme Commision number 3.2.1.21: beta-glucosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC C W28 D45 L99 R113 K146 H147 M190 Y193 D225 W226 S356 E590 W26 D43 L97 R111 K144 H145 M188 Y191 D223 W224 S354 E576
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0008422 beta-glucosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0009251 glucan catabolic process
GO:0030245 cellulose catabolic process

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:3ac0, PDBe:3ac0, PDBj:3ac0
PDBsum3ac0
PubMed20662765
UniProtD1GCC6

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