Structure of PDB 2zy3 Chain C

Receptor sequence
>2zy3C (length=516) Species: 32001 (Alcaligenes faecalis subsp. faecalis) [Search protein sequence]
FELKDELIKIASSDGNRLMLNAGRGNPNFLATTPRRAFFRLGLFAAAESE
LSYSYMTTVGVGGLAKIDGIEGRFERYIAENRDQEGVRFLGKSLSYVRDQ
LGLDPAAFLHEMVDGILGCNYPVPPRMLNISEKIVRQYIIREMGADAIPS
ESVNLFAVEGGTAAMAYIFESLKLNGLLKAGDKVAIGMPVFTPYIEIPEL
AQYALEEVAINADPSLNWQYPDSELDKLKDPAIKIFFCVNPSNPPSVKMD
QRSLERVRNIVAEHRPDLMILTDDVYGTFADDFQSLFAICPENTLLVYSF
SKYFGATGWRLGVVAAHQQNVFDLALDKLQESEKVALDHRYRSLLPDVRS
LKFIDRLVADSRAVALNHTAGLSTPQQVQMALFSLFALMDEADEYKHTLK
QLIRRRETTLYRELGMPPLRDENAVDYYTLIDLQDVTAKLYGEAFSEWAV
KQSSTGDMLFRIADETGIVLLPGRGFGSNRPSGRASLANLNEYEYAAIGR
ALRKMADELYAEYSGQ
3D structure
PDB2zy3 Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.1: aspartate transaminase.
4.1.1.12: aspartate 4-decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP C R37 G173 G174 T175 F204 D286 V288 Y289 S312 S314 K315 R323 R24 G160 G161 T162 F191 D273 V275 Y276 S299 S301 K302 R310
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
GO:0016831 carboxy-lyase activity
GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
GO:0047688 aspartate 4-decarboxylase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006523 alanine biosynthetic process
GO:0006531 aspartate metabolic process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2zy3, PDBe:2zy3, PDBj:2zy3
PDBsum2zy3
PubMed19368885
UniProtQ93QX0|ASDA_COMTE Bifunctional aspartate aminotransferase and L-aspartate beta-decarboxylase (Gene Name=asD)

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