Structure of PDB 2zru Chain C

Receptor sequence
>2zruC (length=356) Species: 2286 (Saccharolobus shibatae) [Search protein sequence]
VEHVEIAAFENVDGLSSSTFLNDVILVHQGFPGISFSEINTKTKFFRKEI
SVPVMVTGMTNELGRINKIIAEVAEKFGIPMGVGSQRVAIEKAEARESFA
IVRKVAPTIPIIANLGMPQLVKGYGLKEFQDAIQMIEADAIAVHLNPAQE
VFQPEGEPEYQIYALEKLRDISKELSVPIIVKESGNGISMETAKLLYSYG
IKNFDTSGQGGTNWIAIEMIRDIRRGNWKAESAKNFLDWGVPTAASIMEV
RYSVPDSFLVGSGGIRSGLDAAKAIALGADIAGMALPVLKSAIEGKESLE
QFFRKIIFELKAAMMLTGSKDVDALKKTSIVILGKLKEWAEYRGINLSIY
EKVRKR
3D structure
PDB2zru New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
ChainC
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.3.2: isopentenyl-diphosphate Delta-isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN C T65 G66 M67 T68 G95 S96 N125 H155 K193 S218 G222 T223 W225 R277 A296 L297 T57 G58 M59 T60 G84 S85 N114 H144 K182 S207 G211 T212 W214 R266 A285 L286 MOAD: Kd=467nM
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004452 isopentenyl-diphosphate delta-isomerase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
GO:0070402 NADPH binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2zru, PDBe:2zru, PDBj:2zru
PDBsum2zru
PubMed19158086
UniProtP61615|IDI2_SACSH Isopentenyl-diphosphate delta-isomerase (Gene Name=fni)

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