Structure of PDB 2y7h Chain C

Receptor sequence
>2y7hC (length=529) Species: 562 (Escherichia coli) [Search protein sequence]
MNNNDLVAKLWKLCDNLRDGGVSYQNYVNELASLLFLKMCKETGQEAEYL
PEGYRWDDLKSRIGQEQLQFYRKMLVHLGEDDKKLVQAVFHNVSTTITEP
KQITALVSNMDSLDWYNGAHGKSRDDFGDMYEGLLQKNANETKSGAGQYF
TPRPLIKTIIHLLKPQPREVVQDPAAGTAGFLIEADRYVKSQTNDLDDLD
GDTQDFQIHRAFIGLELVPGTRRLALMNCLLHDIEGNLDHGGAIRLGNTL
GSDGENLPKAHIVATNPPFGSAAGTNITRTFVHPTSNKQLCFMQHIIETL
HPGGRAAVVVPDNVLFEGGKGTDIRRDLMDKCHLHTILRLPTGIFYAQGV
KTNVLFFTKGTVANPNQDKNCTDDVWVYDLRTNMPSFGKRTPFTDEHLQP
FERVYGEDPHGLSPRTEGEWSFNAEETEVADSEENKNTDQHLATSRWRKF
SREWIRTAKSDSLDISWLKDKDSIDADSLPEPDVLAAEAMGELVQALSEL
DALMRELGASDEADLQRQLLEEAFGGVKE
3D structure
PDB2y7h The Structure of M.Ecoki Type I DNA Methyltransferase with a DNA Mimic Antirestriction Protein.
ChainC
Resolution18.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C Q148 N266 P267 F269 G270 N313 F316 F345 V350 Q148 N266 P267 F269 G270 N313 F316 F345 V350
BS02 SAM C Q148 Y149 A175 G180 F181 E216 N248 T249 N266 P268 T275 F292 Q148 Y149 A175 G180 F181 E216 N248 T249 N266 P268 T275 F292
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation
Cellular Component
GO:0005829 cytosol
GO:0019812 type I site-specific deoxyribonuclease complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2y7h, PDBe:2y7h, PDBj:2y7h
PDBsum2y7h
PubMed19074193
UniProtP08957|T1MK_ECOLI Type I restriction enzyme EcoKI methylase subunit (Gene Name=hsdM)

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