Structure of PDB 2y0f Chain C

Receptor sequence
>2y0fC (length=392) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
MRRPTPTVYVGRVPIGGAHPIAVQSMTNTPTRDVEATTAQVLELHRAGSE
IVRLTVNDEEAAKAVPEIKRRLLAEGVEVPLVGDFHFNGHLLLRKYPKMA
EALDKFRINPGTLHFAEMIRIAMDLGKPVRIGANWGSLDPALLTELMDRN
ASRPEPKSAHEVVLEALVESAVRAYEAALEMGLGEDKLVLSAKVSKARDL
VWVYRELARRTQAPLHLGLTEAGMGVKGIVASAAALAPLLLEGIGDTIRV
SLTPEPRTKEVEVAQEILQALGLRAFAPEVTSCPGCGRTTSTFFQELAEE
VSRRLKERLPEWRARYPGVEELKVAVMGCVVNGPGESKHAHIGISLPGAG
EEPKAPVYADGKLLTILKGEGIAEEFLRLVEDYVKTRFAPKA
3D structure
PDB2y0f Structure of the E-1-Hydroxy-2-Methyl-But-2-Enyl-4-Diphosphate Synthase (Gcpe) from Thermus Thermophilus.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.7.3: (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 C C297 P298 G299 C300 G342 C343 N346 E350 C283 P284 G285 C286 G328 C329 N332 E336
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0141197 4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0016114 terpenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
GO:0044237 cellular metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2y0f, PDBe:2y0f, PDBj:2y0f
PDBsum2y0f
PubMed21167158
UniProtQ72H18|ISPG_THET2 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) (Gene Name=ispG)

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