Structure of PDB 2xxa Chain C

Receptor sequence
>2xxaC (length=409) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
DRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFINRVK
EKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAVVLMA
GLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVG
VDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIK
QVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARG
GAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILGMGDVLSLIED
IESKVDRAQAEKLASKLKKGDGFDLNDFLEQLRQMKNMGGMASLMGDDKV
LVRMEAIINSMTMKERAKPEIIKGSRKRRIAAGSGMQVQDVNRLLKQFDD
MQRMMKKMK
3D structure
PDB2xxa The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor.
ChainC
Resolution3.94 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C K278 A378 N381 S382 M383 T384 M385 S397 R398 R401 G405 S406 G407 K272 A356 N359 S360 M361 T362 M363 S375 R376 R379 G383 S384 G385
BS02 rna C K390 E392 I393 K395 G396 K399 R400 Q411 N414 K368 E370 I371 K373 G374 K377 R378 Q389 N392
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006612 protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0048500 signal recognition particle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2xxa, PDBe:2xxa, PDBj:2xxa
PDBsum2xxa
PubMed21330537
UniProtP0AGD7|SRP54_ECOLI Signal recognition particle protein (Gene Name=ffh)

[Back to BioLiP]