Structure of PDB 2xvh Chain C

Receptor sequence

>2xvhC (length=446) Species: 230105 (Methylophaga aminisulfidivorans) [Search protein sequence]

ATRIAILGAGPSGMAQLRAFQSAQEKGAEIPELVCFEKQADWGGQWNYTW
RTGLDENGEPVHSSMYRYLWSNGPKECLEFADYTFDEHFGKPIASYPPRE
VLWDYIKGRVEKAGVRKYIRFNTAVRHVEFNEDSQTFTVTVQDHTTDTIY
SEEFDYVVCCTGHFSTPYVPEFEGFEKFGGRILHAHDFRDALEFKDKTVL
LVGSSYSAEDIGSQCYKYGAKKLISCYRTAPMGYKWPENWDERPNLVRVD
TENAYFADGSSEKVDAIILCTGYIHHFPFLNDDLRLVTNNRLWPLNLYKG
VVWEDNPKFFYIGMQDQWYSFNMFDAQAWYARDVIMGRLPLPSKEEMKAD
SMAWREKELTLVTAEEMYTYQGDYIQNLIDMTDYPSFDIPATNKTFLEWK
HHKKENIMTFRDHSYRSLMTGTMAPKHHTPWIDALDDSLEAYLSDK

3D structure

PDB

2xvh Structural and Functional Analysis of Bacterial Flavin-Containing Monooxygenase Reveals its Ping-Pong-Type Reaction Mechanism.

Chain

Resolution

2.54 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.14.13.148: trimethylamine monooxygenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	C	G9 G11 P12 S13 E38 K39 Q40 G45 Q46 W47 H63 M66 S72 N73 V126 T162 F165 Q318 S321 F325	G8 G10 P11 S12 E37 K38 Q39 G44 Q45 W46 H62 M65 S71 N72 V125 T161 F164 Q317 S320 F324
BS02	NAP	C	W71 N73 S205 S206 Y207 S208 D211 R229 T230 N246 C271 T272 G273	W70 N72 S204 S205 Y206 S207 D210 R228 T229 N245 C270 T271 G272

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0004497	monooxygenase activity
GO:0004499	N,N-dimethylaniline monooxygenase activity
GO:0042802	identical protein binding
GO:0050660	flavin adenine dinucleotide binding
GO:0050661	NADP binding

View graph for
Molecular Function

External links

PDB	RCSB:2xvh, PDBe:2xvh, PDBj:2xvh
PDBsum	2xvh
PubMed	21527346
UniProt	Q83XK4

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