Structure of PDB 2xuc Chain C

Receptor sequence
>2xucC (length=293) [Search protein sequence]
FSNLAIYWGQGPNQLRLSHFCQETSLDIINIGFINYFPDMSPGHWPGSNF
GNCGSVYVTNDGVVTKSGCHQIMEDIPICQAAGKKVLLSIGGAYPPDQSI
LSEDSAVAFATFLWGAFGPPRPFGDVVVDGFDFDIEHNGGFGYATMVNTF
RQYFNERKFYLSAAPQCIIPDAQLSDAIFNAAFDFIWIQYYNTAACSAKS
FIDTLGTFNFDAWVTVLKASASKDAKLYVGLPASETANQGYYLTPDEVES
LVSTYMDRYPDTFGGIMLWEATASENNQIDGAPYADHMKDILL
3D structure
PDB2xuc Natural Product-Guided Discovery of a Fungal Chitinase Inhibitor.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.14: chitinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XRG C Y34 A124 D172 E174 Q230 Y232 W312 Y7 A93 D134 E136 Q189 Y191 W269 MOAD: ic50=79uM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2xuc, PDBe:2xuc, PDBj:2xuc
PDBsum2xuc
PubMed21168763
UniProtQ873Y0|CHIA1_ASPFM Endochitinase A1 (Gene Name=chiA1)

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