Structure of PDB 2xcu Chain C

Receptor sequence
>2xcuC (length=353) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
HMQFEVLKRFFPKESLKNCKGALWVHTASIGEFNTFLPILKELKREHRIL
LTYFSPRAREYLKTKSDFYDCLHPLPLDNPFSVKRFEELSKPKALIVVER
EFWPSLIIFTKVPKILVNAYAKGSLIEKILSKKFDLIIMRTQEDVEKFKT
FGAKRVFSCGNLKFICQKGKGIKLKGEFIVAGSIHTGEVEIILKAFKEIK
KTYSSLKLILVPRHIENAKIFEKKARDFGFKTSFFENLEGDVILVDRFGI
LKELYPVGKIAIVGGTFVNIGGHNLLEPTCWGIPVIYGPYTHKVNDLKEF
LEKEGAGFEVKNETELVTKLTELLSVKKEIKVEEKSREIKGCYLEKLREF
LRG
3D structure
PDB2xcu Structural and Mechanistic Analysis of the Membrane-Embedded Glycosyltransferase Waaa Required for Lipopolysaccharide Synthesis.
ChainC
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.99.12: lipid IVA 3-deoxy-D-manno-octulosonic acid transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C5P C S182 R212 F247 G248 L250 N273 E276 S183 R213 F248 G249 L251 N274 E277
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0043842 Kdo transferase activity
Biological Process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009244 lipopolysaccharide core region biosynthetic process
GO:0009245 lipid A biosynthetic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2xcu, PDBe:2xcu, PDBj:2xcu
PDBsum2xcu
PubMed22474366
UniProtO66663|KDTA_AQUAE 3-deoxy-D-manno-octulosonic acid transferase (Gene Name=kdtA)

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