Structure of PDB 2wpo Chain C

Receptor sequence
>2wpoC (length=230) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence]
DEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQLSVALPL
NINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSR
GPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEQTTPFKHVALCSVGRRR
GTLAVYGRDPEWVMQRFPDLTAADRDGLRAQWQSGDPFRSDSYGLLGNSV
DAMYIRERLPKLRYDKQLVGVTERESYVKA
3D structure
PDB2wpo Conserved mode of peptidomimetic inhibition and substrate recognition of human cytomegalovirus protease.
ChainC
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H63 S132 S134 H157 R165 R166
Catalytic site (residue number reindexed from 1) H54 S123 S125 H140 R148 R149
Enzyme Commision number 3.4.21.97: assemblin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 01E C E31 H63 S132 L133 S134 S135 K156 C161 V163 G164 R165 I231 E28 H54 S123 L124 S125 S126 K139 C144 V146 G147 R148 I205
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2wpo, PDBe:2wpo, PDBj:2wpo
PDBsum2wpo
PubMed9731777
UniProtP16753|SCAF_HCMVA Capsid scaffolding protein (Gene Name=UL80)

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