Structure of PDB 2w40 Chain C

Receptor sequence
>2w40C (length=502) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
SMNVILSIDQSTQSTKVFFYDEELNIVHSNNLNHEQKCLKPGWYEHDPIE
IMTNLYNLMNEGIKVLKDKYTSVIIKCIGITNQRETVIIWDRITGKPLYN
AIVWLDTRVEELVTEFSAKYNNNDIQKKTGTYFNTYFSAFKILWLIQNNP
EIKQKIDDGTAVIGNINTWLIFNLTKGNCYTDVTNASRTLLMDINTLQWD
EKMCKIFNITNMSVLPEIKSNCSNFGLVKSEHVPDYLNIPITGCIGDQQS
ACIGQAIFDEGEAKCTYGTGVFLLINTGEKVVYSTCGLITTICYKFNDND
KPKYALEGSIGTAGSGVSWLLKNKLIDDPSEASDIMEKCENTTGVIFVPA
FSGLYAPRWRSDARASIYGMTFNTERSHIVRALLEGIAFQLNEIVDSLTS
DMGIEMLHVLRCDGGMTKNKPFMQFNSDIINTKIEVSKYKEVTSLGAAVL
AGLEVKIWDSLDSVKSLLRRSDAVFHSKMDDKKRKKKTSEWNKAVERTLI
QL
3D structure
PDB2w40 Structure and Non-Essential Function of Glycerol Kinase in Plasmodium Falciparum Blood Stages.
ChainC
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.30: glycerol kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOL C R83 E84 W103 Y135 D246 F271 R84 E85 W104 Y136 D247 F272
BS02 GOL C C221 N296 D297 E453 C222 N297 D298 E454
BS03 GOL C L31 N56 E60 L32 N57 E61
BS04 GOL C Y293 K294 F295 D299 K300 Y294 K295 F296 D300 K301
BS05 GOL C K75 V454 K455 K76 V455 K456
BS06 GOL C E200 K204 I208 M211 E201 K205 I209 M212
Gene Ontology
Molecular Function
GO:0004370 glycerol kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006071 glycerol metabolic process
GO:0006072 glycerol-3-phosphate metabolic process
GO:0006641 triglyceride metabolic process
GO:0016310 phosphorylation
GO:0019563 glycerol catabolic process
GO:0046167 glycerol-3-phosphate biosynthetic process
Cellular Component
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2w40, PDBe:2w40, PDBj:2w40
PDBsum2w40
PubMed19040641
UniProtQ8IDI4

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