Structure of PDB 2uzk Chain C

Receptor sequence
>2uzkC (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
MGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGW
KNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAP
3D structure
PDB2uzk Crystal Structure of the Human Foxo3A-Dbd/DNA Complex Suggests the Effects of Post-Translational Modification.
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C M1157 S1161 Y1162 N1208 P1247 M1 S5 Y6 N52 P91
BS02 dna C L1180 R1211 H1212 S1215 R1222 S1232 W1234 L24 R55 H56 S59 R66 S76 W78
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2uzk, PDBe:2uzk, PDBj:2uzk
PDBsum2uzk
PubMed17940099
UniProtO43524|FOXO3_HUMAN Forkhead box protein O3 (Gene Name=FOXO3)

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