Structure of PDB 2pzv Chain C

Receptor sequence
>2pzvC (length=123) Species: 303 (Pseudomonas putida) [Search protein sequence]
NLPTAQEVQGLMARYIELVDVGDIEAIVQMYADDATVENPFGQPPIHGRE
QIAAFYRQGLKVRACLTGPVRASHNGCGAMPFRVEMVWNGQPCALDVIDV
MRFDEHGRIQTMQAYWSEVNLSV
3D structure
PDB2pzv Testing Electrostatic complementarity in Enzyme Catalysis: Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole
ChainC
Resolution1.25 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) Y16 N40 D100 D103
Catalytic site (residue number reindexed from 1) Y15 N39 D96 D99
Enzyme Commision number 5.3.3.1: steroid Delta-isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IPH C Y16 N40 F86 D103 Y15 N39 F82 D99 MOAD: Kd=135uM
Gene Ontology
Molecular Function
GO:0004769 steroid delta-isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0008202 steroid metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2pzv, PDBe:2pzv, PDBj:2pzv
PDBsum2pzv
PubMed16602823
UniProtP07445|SDIS_PSEPU Steroid Delta-isomerase (Gene Name=ksi)

[Back to BioLiP]