Structure of PDB 2pxy Chain C

Receptor sequence
>2pxyC (length=183) Species: 10090 (Mus musculus) [Search protein sequence]
DDIEADHVGSYGIVVYQSPGDIGQYTFEFDGDELFYVDLDKKETIWMLPE
FAQLRSFDPQGGLQNIATGKHNLGVLTKRSNSTPATNEAPQATVFPKSPV
LLGQPNTLICFVDNIFPPVINITWLRNSKSVADGVYETSFFVNRDYSFHK
LSYLTFIPSDDDIYDCKVEHWGLEEPVLKHWEP
3D structure
PDB2pxy Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'.
ChainC
Resolution2.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C Y9 V11 F24 S53 F54 N62 T65 N69 V72 Y11 V14 F27 S56 F57 N65 T68 N72 V75
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:2pxy, PDBe:2pxy, PDBj:2pxy
PDBsum2pxy
PubMed17694060
UniProtP14438|HA2U_MOUSE H-2 class II histocompatibility antigen, A-U alpha chain (Fragment) (Gene Name=H2-Aa)

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