Structure of PDB 2pnx Chain C

Receptor sequence
>2pnxC (length=51) Species: 9606 (Homo sapiens) [Search protein sequence]
NEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCS
Q
3D structure
PDB2pnx ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation
ChainC
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C Y198 S205 Y206 G207 E208 M209 I210 G211 C212 E220 W221 K232 P233 G235 Y5 S12 Y13 G14 E15 M16 I17 G18 C19 E27 W28 K39 P40 G42
BS02 ZN C C199 C201 H223 C226 C6 C8 H30 C33
BS03 ZN C C212 C217 C239 C242 C19 C24 C46 C49
External links
PDB RCSB:2pnx, PDBe:2pnx, PDBj:2pnx
PDBsum2pnx
PubMed19187765
UniProtQ9UNL4|ING4_HUMAN Inhibitor of growth protein 4 (Gene Name=ING4)

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