Structure of PDB 2pc9 Chain C

Receptor sequence
>2pc9C (length=517) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
RLEALGIHPKKRVFWNTVSPVLVEHTLLRGEGLLAHHGPLVVDTTPYTGR
SPKDKFVVREPEVEGEIWWGEVNQPFAPEAFEALYQRVVQYLSERDLYVQ
DLYAGADRRYRLAVRVVTESPWHALFARNMFILPRRFGNVEAFVPGFTVV
HAPYFQAVPERDGTRSEVFVGISFQRRLVLIVGTKYAGEIKKSIFTVMNY
LMPKRGVFPMHASANVGKEGDVAVFFGLSGTGKTTLSTDPERPLIGDDEH
GWSEDGVFNFEGGCYAKVIRLSPEHEPLIYKASNQFEAILENVVVNPESR
RVQWDDDSKTENTRSSYPIAHLENVVESGVAGHPRAIFFLSADAYGVLPP
IARLSPEEAMYYFLSGYTARVTEPRATFSACFGAPFLPMHPGVYARMLGE
KIRKHAPRVYLVNTGWTGGPYGVGYRFPLPVTRALLKAALSGALENVPYR
RDPVFGFEVPLEAPGVPQELLNPRETWADKEAYDQQARKLARLFQENFQK
YASGVAKEVAEAGPRTE
3D structure
PDB2pc9 Crystal Structure Of ATP-Dependent Phosphoenolpyruvate Carboxykinase From Thermus thermophilus HB8
ChainC
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R52 K197 H216 S234 K238 T239 D253 R319
Catalytic site (residue number reindexed from 1) R50 K192 H211 S229 K233 T234 D248 R314
Enzyme Commision number 4.1.1.49: phosphoenolpyruvate carboxykinase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C R130 N131 F133 G267 R128 N129 F131 G262
BS02 ATP C S234 G235 T236 G237 K238 T239 T240 K272 T426 R438 F439 L441 T444 S229 G230 T231 G232 K233 T234 T235 K267 T414 R426 F427 L429 T432
Gene Ontology
Molecular Function
GO:0004611 phosphoenolpyruvate carboxykinase activity
GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity
GO:0005524 ATP binding
GO:0016831 carboxy-lyase activity
GO:0017076 purine nucleotide binding
GO:0046872 metal ion binding
Biological Process
GO:0006094 gluconeogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:2pc9, PDBe:2pc9, PDBj:2pc9
PDBsum2pc9
PubMed
UniProtQ5SLL5|PCKA_THET8 Phosphoenolpyruvate carboxykinase (ATP) (Gene Name=pckA)

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