Structure of PDB 2p3n Chain C

Receptor sequence
>2p3nC (length=256) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
MDRLDFSIKLLRKVGHLLMIHWGRVDNVEKKTGFKDIVTEIDREAQRMIV
DEIRKFFPDENIMAEEGIFEKGDRLWIIDPIDGTINFVHGLPNFSISLAY
VENGEVKLGVVHAPALNETLYAEEGSGAFFNGERIRVSENASLEECVGST
GSYVDFTGKFIERMEKRTRRIRILGSAALNAAYVGAGRVDFFVTWRINPW
DIAAGLIIVKEAGGMVTDFSGKEANAFSKNFIFSNGLIHDEVVKVVNEVV
EEIGGK
3D structure
PDB2p3n Crystal structure of the tetrameric inositol 1-phosphate phosphatase (TM1415) from the hyperthermophile, Thermotoga maritima.
ChainC
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D1079 I1081 D1082 T1084 D1201
Catalytic site (residue number reindexed from 1) D79 I81 D82 T84 D201
Enzyme Commision number 3.1.3.11: fructose-bisphosphatase.
3.1.3.25: inositol-phosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C E1065 D1079 I1081 E65 D79 I81
Gene Ontology
Molecular Function
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0016787 hydrolase activity
GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity
GO:0046872 metal ion binding
GO:0052832 inositol monophosphate 3-phosphatase activity
GO:0052833 inositol monophosphate 4-phosphatase activity
GO:0052834 inositol monophosphate phosphatase activity
Biological Process
GO:0006020 inositol metabolic process
GO:0007165 signal transduction
GO:0046854 phosphatidylinositol phosphate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2p3n, PDBe:2p3n, PDBj:2p3n
PDBsum2p3n
PubMed17419729
UniProtO33832|BSUHB_THEMA Fructose-1,6-bisphosphatase/inositol-1-monophosphatase (Gene Name=suhB)

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