Structure of PDB 2oyi Chain C

Receptor sequence
>2oyiC (length=299) Species: 9606 (Homo sapiens) [Search protein sequence]
YEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQI
HDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQ
KRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYA
LRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDF
GDAPSAKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLN
GVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
3D structure
PDB2oyi Probing the gamma2 Calcium-Binding Site: Studies with gammaD298,301A Fibrinogen Reveal Changes in the gamma294-301 Loop that Alter the Integrity of the "a" Polymerization Site.
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C F295 T305 F322 Q329 D330 K338 C339 H340 Y363 D364 F200 T210 F227 Q234 D235 K243 C244 H245 Y268 D269
BS02 CA C D318 D320 F322 E323 G324 D223 D225 F227 E228 G229
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2oyi, PDBe:2oyi, PDBj:2oyi
PDBsum2oyi
PubMed17411074
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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