Structure of PDB 2nzy Chain C

Receptor sequence
>2nzyC (length=351) Species: 210 (Helicobacter pylori) [Search protein sequence]
MFQPLLDAYVESASIEKMASKSPPPLKIAVANWWGDEEIKEFKNSVLYFI
LSQRYTITLHQNPNEFSDLVFGNPLGSARKILSYQNAKRVFYTGENESPN
FNLFDYAIGFDELDFNDRYLRMPLYYDRLHHKAESVNDTTAPYKLKDNSL
YALKKPSHCFKEKHPNLCAVVNDESDPLKRGFASFVASNPNAPIRNAFYD
ALNSIEPVTGGGSVRNTLGYNVKNKNEFLSQYKFNLCFENTQGYGYVTEK
IIDAYFSHTIPIYWGSPSVAKDFNPKSFVNVHDFKNFDEAIDYIKYLHTH
KNAYLDMLYENPLNTLDGKAYFYQNLSFKKILAFFKTILENDTIYHDNPF
I
3D structure
PDB2nzy Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
ChainC
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.152: 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC C G94 L124 N240 Y246 T248 E249 K250 G94 L124 N240 Y246 T248 E249 K250
BS02 GDP C V186 A187 S188 N189 R195 V222 K225 E249 K250 V186 A187 S188 N189 R195 V222 K225 E249 K250
Gene Ontology
Molecular Function
GO:0008417 fucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2nzy, PDBe:2nzy, PDBj:2nzy
PDBsum2nzy
PubMed17251184
UniProtO30511|FUCT_HELPX Alpha-(1,3)-fucosyltransferase FucT (Gene Name=fucT)

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