Structure of PDB 2i54 Chain C

Receptor sequence
>2i54C (length=242) Species: 5665 (Leishmania mexicana) [Search protein sequence]
KAILLFDVDGTLTPPRNPETHDMKEALLKARAAGFKLGVVGGSDFAKQKE
QLGESILEDFDYVFSENGLLAYKDGKEFHRNSLLRALGNEKVVAFVKKCL
HLIADLDIPVQRGTFVEFRNGMFNVSPIGRNCSQQERDEFENLDKERHIR
EKLIRELKEAFPDYQLAYSVGGQISFDVFPKGWDKTYCLQFVENDFETIH
FFGDKTSEGGNDYEIFTDSRTIGHSVKTYKDTIAILEALLED
3D structure
PDB2i54 Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.4.2.8: phosphomannomutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C D10 D12 D207 D7 D9 D204
Gene Ontology
Molecular Function
GO:0004615 phosphomannomutase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006013 mannose metabolic process
GO:0006487 protein N-linked glycosylation
GO:0009298 GDP-mannose biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2i54, PDBe:2i54, PDBj:2i54
PDBsum2i54
PubMed16963079
UniProtQ95ZD7

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