Structure of PDB 2hlo Chain C

Receptor sequence
>2hloC (length=292) Species: 9606 (Homo sapiens) [Search protein sequence]
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGK
DCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGS
VDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELE
DWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSD
KFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQG
GTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
3D structure
PDB2hlo ?
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C F295 T305 F322 Q329 K338 C339 H340 Y363 D364 F194 T204 F221 Q228 K237 C238 H239 Y262 D263
BS02 CA C D318 D320 F322 G324 D217 D219 F221 G223
BS03 CA C D294 G296 D298 D301 D193 G195 D197 D200
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2hlo, PDBe:2hlo, PDBj:2hlo
PDBsum2hlo
PubMed
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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