Structure of PDB 2hdx Chain C

Receptor sequence
>2hdxC (length=108) Species: 10090 (Mus musculus) [Search protein sequence]
QPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGECVLTFN
FQGKAKHLRLSLNAAGQCRVQHLHFQSIFDMLEHFRVHPIPLESGGSSDV
VLVSYVPS
3D structure
PDB2hdx Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
ChainC
Resolution2.35 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C R534 R555 R560 K575 H576 R578 Q590 H591 P610 L611 E612 R15 R36 R41 K56 H57 R59 Q71 H72 P91 L92 E93
Gene Ontology
Molecular Function
GO:0035591 signaling adaptor activity
Biological Process
GO:0007165 signal transduction

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2hdx, PDBe:2hdx, PDBj:2hdx
PDBsum2hdx
PubMed16824542
UniProtQ91ZM2|SH2B1_MOUSE SH2B adapter protein 1 (Gene Name=Sh2b1)

[Back to BioLiP]