Structure of PDB 2gfe Chain C

Receptor sequence
>2gfeC (length=260) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKY
KLTIVGDGKYGARDEDTKIWNGMVGELVYGKADIAIAPLTITLVREEVID
FSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDDGSTKEFFRRSK
IAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIE
QRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLK
NKWWYDKGEC
3D structure
PDB2gfe Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate.
ChainC
Resolution1.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C E42 H46 E41 H45
BS02 GLU C Y61 L90 T91 R96 G141 S142 T143 E193 Y60 L89 T90 R95 G140 S141 T142 E192
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:2gfe, PDBe:2gfe, PDBj:2gfe
PDBsum2gfe
PubMed16855092
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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