Structure of PDB 2gd4 Chain C

Receptor sequence
>2gd4C (length=418) Species: 9606 (Homo sapiens) [Search protein sequence]
PVDICTAKPRDIPMNPMCIYRSPEQKIPEATNRRVWELSKANSRFATTFY
QHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISE
KTSDQIHFFFAKLNCRLYRKANKASKLVSANRLFGDKSLTFNETYQDISE
LVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVL
VLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRV
AEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEE
MMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPAASALPGIVAEGRDDLY
VSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIR
EVPLNTIIFMGRVANPCV
3D structure
PDB2gd4 Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation.
ChainC
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZDO C E113 K114 E100 K101
BS02 SUS C K11 P12 N45 K114 F122 K8 P9 N32 K101 F109
BS03 BDP C N45 K125 N32 K112
BS04 SGN C T44 N45 R129 T31 N32 R116
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0030193 regulation of blood coagulation
Cellular Component
GO:0005615 extracellular space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2gd4, PDBe:2gd4, PDBj:2gd4
PDBsum2gd4
PubMed16619025
UniProtP01008|ANT3_HUMAN Antithrombin-III (Gene Name=SERPINC1)

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