Structure of PDB 2fbw Chain C

Receptor sequence
>2fbwC (length=139) Species: 9031 (Gallus gallus) [Search protein sequence]
ATTAKEEMARFWEKNTKSSRPLSPHISIYKWSLPMAMSITHRGTGVALSL
GVSLFSLAALLLPEQFPHYVAVVKSLSLSPALIYSAKFALVFPLSYHTWN
GIRHLVWDMGKGFKLSQVEQSGVVVLILTLLSSAAIAAM
3D structure
PDB2fbw 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme.
ChainC
Resolution2.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM C H42 R43 G46 L49 S50 H98 H105 H41 R42 G45 L48 S49 H97 H104
BS02 CBE C S39 I40 R43 S38 I39 R42
Gene Ontology
Molecular Function
GO:0009055 electron transfer activity
GO:0046872 metal ion binding
Biological Process
GO:0006099 tricarboxylic acid cycle
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2fbw, PDBe:2fbw, PDBj:2fbw
PDBsum2fbw
PubMed16371358
UniProtD0VWW3

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