Structure of PDB 2el9 Chain C

Receptor sequence
>2el9C (length=372) Species: 562 (Escherichia coli) [Search protein sequence]
KNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLF
KRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
QRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWW
RALGISEHVTLELNSIGSLEARANYRDAGDYLDEESREHFAGLCKLLESA
GIAYTVNQRLVRGLDYYNRTVFEWVTNGTVCAGGRYDGLVEQLGGRATPA
VGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLR
DELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDL
RSGEQTAVAQDSVAAHLRTLLG
3D structure
PDB2el9 Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.21: histidine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HSS C T85 R113 G120 Y122 F125 Q127 E131 R259 Y263 Y264 T281 V282 G304 F305 G308 R311 T83 R111 G118 Y120 F123 Q125 E129 R212 Y216 Y217 T229 V230 G252 F253 G256 R259
Gene Ontology
Molecular Function
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004821 histidine-tRNA ligase activity
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006412 translation
GO:0006427 histidyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:2el9, PDBe:2el9, PDBj:2el9
PDBsum2el9
PubMed
UniProtP60906|SYH_ECOLI Histidine--tRNA ligase (Gene Name=hisS)

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