Structure of PDB 2ce8 Chain C

Receptor sequence
>2ce8C (length=337) Species: 9606 (Homo sapiens) [Search protein sequence]
DYFQGAMGSKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNH
GEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYI
RSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAIS
PDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWT
GGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEV
LHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASI
FQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
3D structure
PDB2ce8 Molecular Recognition of Transcriptional Repressor Motifs by the Wd Domain of the Groucho/Tle Corepressor.
ChainC
Resolution2.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C V486 C488 Y532 R534 E550 Y578 S594 D617 L636 F661 V53 C55 Y99 R101 E117 Y145 S161 D184 L203 F228
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Biological Process

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Cellular Component
External links
PDB RCSB:2ce8, PDBe:2ce8, PDBj:2ce8
PDBsum2ce8
PubMed16762837
UniProtQ04724|TLE1_HUMAN Transducin-like enhancer protein 1 (Gene Name=TLE1)

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