Structure of PDB 2c8m Chain C

Receptor sequence
>2c8mC (length=245) Species: 273075 (Thermoplasma acidophilum DSM 1728) [Search protein sequence]
MEGRLLLLETPGNTRMSLAYDEAIYRSFQYGDKPILRFYRHDRSVIIGYF
QVAEEEVDLDYMKKNGIMLARRYTGGGAVYHDLGDLNFSVVRSSDDMDIT
SMFRTMNEAVVNSLRILGLDARPGELNDVSIPVNKKTDIMAGEKKIMGAA
GAMRKGAKLWHAAMLVHTDLDMLSAVLKSTRERVANVTDFVDVSIDEVRN
ALIRGFSETLHIDFREDTITEKEESLARELFDKKYSTEEWNMGLL
3D structure
PDB2c8m Structure of a Putative Lipoate Protein Ligase from Thermoplasma Acidophilum and the Mechanism of Target Selection for Post-Translational Modification.
ChainC
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.1.20: lipoate--protein ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LPA C R72 V79 H81 K145 G148 A149 H161 A162 R72 V79 H81 K145 G148 A149 H161 A162
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016979 lipoate-protein ligase activity
GO:0017118 lipoyltransferase activity
GO:0031405 lipoic acid binding
GO:0046872 metal ion binding
Biological Process
GO:0009249 protein lipoylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2c8m, PDBe:2c8m, PDBj:2c8m
PDBsum2c8m
PubMed16384580
UniProtQ9HKT1|LPLAN_THEAC Lipoate-protein ligase A subunit 1 (Gene Name=lplA)

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