Structure of PDB 2c47 Chain C

Receptor sequence
>2c47C (length=283) Species: 9606 (Homo sapiens) [Search protein sequence]
FRVGKKIELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEG
VPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLIT
RMEYVHTKSLIYRDVKPENFLVGRPGQHAIHIIDFGLAKEYIDPETKKHI
PYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQG
LKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPD
YDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTP
3D structure
PDB2c47 The Structure of Casein Kinase 1 Gamma 2
ChainC
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D165 K167 T215
Catalytic site (residue number reindexed from 1) D114 K116 T161
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5ID C L60 L122 S125 E169 L172 I187 L9 L71 S74 E118 L121 I133
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2c47, PDBe:2c47, PDBj:2c47
PDBsum2c47
PubMed
UniProtP78368|KC1G2_HUMAN Casein kinase I isoform gamma-2 (Gene Name=CSNK1G2)

[Back to BioLiP]